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 Formulary Chapter 1: Gastro-intestinal system - Full Chapter
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01.06.07  Expand sub section  Other drugs used in constipation
Linaclotide (Constella▼)
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Formulary
Amber
  • For moderate to severe IBS-Constipation.
  • For patients who have not responded adequately to or cannot tolerate all other suitable treatment options BUT BEFORE other agents with higher costs.
 
   
Prucalopride (Resolor )
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Formulary
Amber

Available for use in men and women for chronic constipation.

Use in men approved following review in March 2018

 
Link  NICE TA211: Constipation (women) - prucalopride
   
 ....
 Non Formulary Items
Lubiprostone  (Amitiza▼ )

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Non Formulary
Black

Manufacturer has now discontinued the product

Restricted to gastroenterology consultant initiation in line with NICE TA 318.

GPs may continue the prescribing when a review after 2 weeks therapy demonstrates benefit.

Link  NICE TA318: Lubiprostone for treating chronic idiopathic constipation
 
  
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Section Title Section Title (top level)
Section Title Section Title (sub level)
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Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
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Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Medicines which are suitable for initiation and maintenance prescribing by primary and secondary care clinicians. These medicines should be initiated and prescribed within their licensed indications.  

Amber

Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate, or initiation and maintenance of prescribing in Primary Care following recommendation from a Specialist.

Some amber medicines require agreement with the local (internal) medicines committee prior to initiation; others may require a framework to support safe transfer and maintenance of care such as a RICaD or ESCA. The Formulary will be annotated to reflect these requirements.   

Red

Medicines for initiation and maintenance prescribing by Specialists only  

Black

Non-formulary medicines- medicines not recommended for routine primary care prescribing.  

Grey

Positive NICE TA and /or awaiting local clarification on place in therapy ; Please contact your Medicines Optimisation team for more information.  

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