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 Formulary Chapter 6: Endocrine system - Full Chapter
Notes:

This chapter is mostly updated. The section still outstanding is 6.4.1.1 (oestrogens and HRT). 

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06.01  Expand sub section  Drugs used in diabetes
06.01.01  Expand sub section  Insulins
06.01.01.01  Expand sub section  Short-acting insulins
Insulin (Actrapid®)
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Formulary
Green
 
   
Insulin (Humulin® S)
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Formulary
Green
 
   
Insulin (Insuman® Rapid)
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Formulary
Green
 
   
Insulin Aspart (Fiasp®)
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Formulary
Red

For specialist use in pregnancy

 
   
Insulin Aspart  (NovoRapid®)
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Formulary
Green
 
   
Insulin Glulisine (Apidra®)
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Formulary
Green
 
   
Insulin Lispro 100 units/mL (Humalog 100 units/mL ®)
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Formulary
Green
 
   
06.01.01.02  Expand sub section  Intermediate- and long-acting insulins
Insulin detemir (Levemir®)
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Formulary
Green
 
   
Insulin glargine 100 units/mL biosimilar (Abasaglar®)
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Formulary
Green
  • Prescribe by brand as recommended by MHRA.

  • First line for new patients initiated on insulin glargine 100 units/mL
  • Substitution and automatic switching from Lantus® to Abasaglar®CANNOT BE UNDERTAKEN.  
  • Link  Answers to commonly asked questions about biosimilar versions of insulin glargine
    Link  Risk Assessment- High Strength Insulins/ Biosimilars/ Fixed Combination
       
    Insulin glargine 100 units/mL (Lantus®)
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    Formulary
    Green
    £

  • Prescribe by brand 
  •    
    Insulin glargine 300 units/mL (Toujeo®)
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    Formulary
    Amber
    Prescribe by brand

  • Reconsidered and approved in April 2017
  • Specialist initiation.
  • Supported by RICaD

  • For patients who require more than 80 units of insulin glargine per day and who are troubled by nocturnal hypos. Transfer to Primary Care should not happen until specialists can demonstrate reduction in nocturnal hypos (e.g. after 3-4 months).  
  • Link  Risk Assessment- High Strength Insulins/ Biosimilars/ Fixed Combination
       
    Isophane Insulin (Humulin® I)
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    Formulary
    Green
     
       
    Isophane Insulin (Insulatard®)
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    Formulary
    Green
     
       
    Isophane Insulin (Insuman® Basal)
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    Formulary
    Green
     
       
    Insulin degludec 100 units/mL (Tresiba®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
    • To avoid the use of an insulin pump in patients with Type 1 diabetes who have nocturnal/severe hypoglycaemia as defined in NICE TA 151 OR recurrent DKA despite good compliance with current insulin regime
    • Specialist initiation
    • Supported by a RICaD, see link below.
     
    Link  RICaD: Insulin degludec
       
    Insulin degludec 100 units/mL (Tresiba®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
    • Specialist use only
    • For the treatment of patients with Type 2 diabetes who have nocturnal / severe hypoglycaemia or those with recurrent hypoglycaemic episodes requiring hospital admission

     

     
       
    06.01.01.02  Expand sub section  Biphasic insulins to top
    Biphasic Insulin Aspart (NovoMix® 30)
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    Formulary
    Green
     
       
    Biphasic Insulin Lispro (Humalog® Mix)
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    Formulary
    Green
  • Humalog Mix25
  • Humalog Mix50 
  •    
    Biphasic Isophane Insulin (Humulin® M3)
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    Formulary
    Green
     
       
    Biphasic Isophane Insulin (Insuman® Comb)
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    Formulary
    Green
  • Insuman Comb 15
  • Insuman Comb 25
  • Insuman Comb 50 
  •    
    06.01.02  Expand sub section  Antidiabetic drugs
    06.01.02.01  Expand sub section  Sulphonyureas
    Gliclazide
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    First Choice
    Green
     
    Gliclazide M/R
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    Second Choice
    Green
     
       
    Glibenclamide
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    Formulary
    Amber
  • For patients who do not want to move to insulin but not responding to metformin
  • Use in pregnancy as per NICE 
  • Link  NICE NG 3: Diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period
       
    Glimepiride
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    Formulary
    Green
     
       
    06.01.02.02  Expand sub section  Biguanides
    Metformin
    (Standard release tablets)
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    First Choice
    Green
     
    Metformin M/R
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    Second Choice
    Green
  • Only for patients intolerant of slowly titrated standard release metformin 
  •    
    Metformin oral solution SF
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    Second Choice
    Green
  • For patients with swallowing difficulties £££ 
  •    
    06.01.02.03  Expand sub section  Other antidiabetic drugs
    06.01.02.03  Expand sub section  DPP-4 inhibitors to top
    06.01.02.03  Expand sub section  Alpha glucosidase inhibitors
    06.01.02.03  Expand sub section  GLP-1 mimetics
    06.01.02.03  Expand sub section  DPP4 inhibitors (gliptins)
    Alogliptin (Vipidia▼®)
    View adult BNF View SPC online View childrens BNF
    First Choice
    Green
     
    Linagliptin (Trajenta®)
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    Formulary
    Green
    In line with NICE 
       
    Sitagliptin (Januvia®)
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    Formulary
    Green
    In line with NICE 
       
    06.01.02.03  Expand sub section  SGLT2 inhibitors
    Canagliflozin (Invokana▼®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
    SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

    In line with NICE 
    Link  NICE TA315: Canagliflozin in combination therapy for treating type 2 diabetes (June 2014)
    Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes (May 2016)
       
    Dapagliflozin (Forxiga▼®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
    SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

    In line with NICE 
    Link  NICE TA288: Dapagliflozin in combination therapy for treating type 2 diabetes (June 2013)
    Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes (May 2016)
    Link  NICE TA418: Dapagliflozin in triple therapy for treating type 2 diabetes (November 2016)
       
    Empagliflozin (Jardiance▼®)
    ( View adult BNF View SPC online View childrens BNF
    Formulary
    Green
    SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

    In line with NICE
     
    Link  NICE TA336: Empagliflozin in combination therapy for treating type 2 diabetes (Mar 2015)
    Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes (May 2016)
       
    06.01.02.03  Expand sub section  GLP1 agonists to top
    Dulaglutide (Trulicity®)
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    Formulary
    Green
  • NOT for monotherapy
  • NOT in combination with insulin 
  •    
    Exenatide (Byetta®)
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    Formulary
    Green
    In line with NICE guidance 
    Link  NICE NG28: Type 2 diabetes in adults: management (Dec 2015)
       
    Exenatide prolonged release (Bydureon®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
     
    Link  NICE NG28:Type 2 diabetes in adults: management (Dec 2015)
       
    Liraglutide (Victoza®)
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    Formulary
    Green
  • For the treatment of type 2 diabetes ONLY.
  • In line with NICE 
  • Link  NICE NG28: Type 2 diabetes in adults: management (Dec 2015)
       
    Lixisenatide (Lyxumia®)
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    Formulary
    Green
  • 1st line GLP1 for co-prescribing with insulin
  • Supported by a RICaD (in development)
     
  •    
    06.01.02.03  Expand sub section  Meglitinides
    Repaglinide
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    Formulary
    Green
     
       
    06.01.02.03  Expand sub section  SGL2 inhibitors
    06.01.02.03  Expand sub section  Other
    06.01.02.03  Expand sub section  Thiazolidinediones
    Pioglitazone
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    Formulary
    Green
     
       
    06.01.02.05  Expand sub section  Glucagon-like peptide-1 receptor agonists - once weekly to top
    06.01.02.07  Expand sub section  Other antidiabetic drugs
    06.01.03  Expand sub section  Diabetic ketoacidosis
    06.01.04  Expand sub section  Treatment of hypoglycaemia
    Glucagon (GlucaGen® HypoKit)
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    Formulary
    Green
     
       
    GlucoGel®
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    Formulary
    Green
     
       
    Treatment of hypoglycaemia (Rapilose® gel)
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    Formulary
    Green
     
       
    06.01.04  Expand sub section  Chronic hypoglycaemia
    06.01.05  Expand sub section  Treatment of diabetic nephropathy and neuropathy to top
    06.01.05  Expand sub section  Diabetic nephropathy
    06.01.05  Expand sub section  Diabetic neuropathy
    06.01.06  Expand sub section  Diagnostic and monitoring agents for diabetes mellitus
    06.01.06  Expand sub section  Blood glucose monitoring
    Blood Glucose Meters
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    Formulary
    Green
     
       
    06.01.06  Expand sub section  Urinalysis to top
    06.01.06  Expand sub section  Oral glucose tolerance test
    06.02  Expand sub section  Thyroid and Antithyroid drugs
    06.02.01  Expand sub section  Thyroid hormones
    Levothyroxine
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    Formulary
    Green
     
       
    Liothyronine
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    Formulary
    Red
  • Tablets
  • Injection 
  •    
    06.02.02  Expand sub section  Antithyroid drugs
    Carbimazole
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    Formulary
    Green
     
       
    Propylthiouracil
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    Formulary
    Green
     
       
    Iodine and Iodide
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    Formulary
    Red
  • Potassium iodide tablets 65mg
  • Potassium iodate 85mg
  • Aqueous Iodine Oral solution  
  •    
    06.03  Expand sub section  Corticosteroids to top
    06.03.01  Expand sub section  Replacement therapy
    Fludrocortisone
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    Formulary
    Green
     
       
    06.03.02  Expand sub section  Glucocorticoid therapy
    Betamethasone
    (parenteral)
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    Formulary
    Red
     
       
    Dexamethasone
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    Formulary
    Green
  • Tablets £££
  • Oral solution SF £££ 
  •    
    Dexamethasone phosphate injection
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    Formulary
    Red
     
       
    Hydrocortisone
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    Formulary
    Green
  • Standard release tablets only 
  •    
    Hydrocortisone sodium succinate (Solu-Cortef®)
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    Formulary
    Green
     
       
    Methylprednisolone acetate injection (Depo-Medrone® )
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    Formulary
    Green
     
    Link  See chapter 10
       
    Methylprednisolone sodium succinate injection (Solu-Medrone ®)
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    Formulary
    Red
     
       
    Methylprednisolone tablets
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    Formulary
    Red
    In line with NICE 
    Link  NICE CG186: Multiple Sclerosis in adults; management
       
    Prednisolone
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    Formulary
    Green
  • Plain tablets 
  • Link  UKMI Q&A: Is there any evidence to support the use of enteric coated (EC) over uncoated prednisolone tablets?
       
    Triamcinolone (Kenalog®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
     
    Link  See Chapter 10
       
    06.03.02  Expand sub section  Disadvantages of corticosteroids
    06.03.02  Expand sub section  Use of corticosteroids
    06.03.02  Expand sub section  Pregnancy and breastfeeding to top
    06.03.02  Expand sub section  Administration
    06.03.02  Expand sub section  Withdrawal of corticosteroids
    06.04  Expand sub section  Sex hormones
    06.04.01  Expand sub section  Female sex hormones and their modulators
    06.04.01.01  Expand sub section  Oestrogens and HRT to top
    Tibolone (Livial®)
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    Formulary
    Green
    Second line 
       
    06.04.01.01  Expand sub section  Hormone replacement therapy
    06.04.01.01  Expand sub section  Ethinylestradiol
    Ethinylestradiol tablets
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    Formulary
    Red
  • For induction of puberty in female patients who cannot tolerate or are allergic to first-line patches.

  • 2 mcg- unlicensed special
  • 10 mcg ££  
  •    
    06.04.01.01  Expand sub section  Raloxifene
    Raloxifene Hydrochloride (Evista®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
    In line with NICE 
    Link  NICE TA160: quick reference guide on osteoporosis
       
    06.04.01.02  Expand sub section  Progestogens
    Medroxyprogesterone Acetate
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
  • Climanor®
  • Provera® 
  •    
    Norethisterone
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
     
       
    Progesterone (Crinone®)
    (vaginal gel)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Progesterone (Cyclogest®)
    (pessaries)
    View adult BNF View SPC online View childrens BNF
    Formulary Amber Traffic Light  Recurrent miscarriage (off label use)


    Red Traffic Light  Fertility (off label use)

     
       
    Progesterone (micronised) (Utrogestan®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • Supported by a RICaD
     
  •    
    Ulipristal acetate (Esmya®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • The only indication approved for use by the APC is
    pre-operative treatment of moderate to severe symptoms of uterine fibroids (1 course).
  • Supported by an ESCA, see link below.
  • Currently only one course (3 months) covered by ESCA 
  • Link  ESCA: Ulipristal acetate (Esmya)
    Link  MHRA alert Feb 2018: do not initiate treatment in new users or those between treatment courses;monitor liver function in current and recent users
       
    06.04.02  Expand sub section  Male sex hormones and antagonists to top
    Testosterone gel
    (Transdermal preparations)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • Testim
  • Testogel
  • Tostran

  • use in women with low libido approved by APC (unlicensed). Specialist to initiate and issue first supply.
     
  •    
    Testosterone injection (Sustanon 250®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
     
       
    Testosterone undecanoate injection
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
     
       
    Testosterone undecanoate oral (Restandol Testocaps®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • For paediatric directorate only
  • For induction of puberty  
  •    
    Testosterone implants
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.04.02  Expand sub section  Anti-androgens
    Finasteride (5mg tablets)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
  • In men only 
  •    
    Dutasteride (Avodart®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
    High Cost Medicine
  • supported by a RICaD (in development)
  • When finasteride has failed or is contraindicated/not tolerated 
  •    
    Cyproterone Acetate
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
     
       
    Finasteride (1mg tablets)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Hyperandrogenism in women
    Not NHS Not NHS 
  • Link  Link to section 13.9
       
    06.04.03  Expand sub section  Anabolic steroids
    Nandrolone (Deca-Durabolin®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Hospital only 
  •    
    Oxandrolone Tablets 2.5 mg
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.04.04  Expand sub section  Gender dysphoria
    06.05  Expand sub section  Hypothalamic and pituitary hormones and anti-oestrogens
    06.05.01  Expand sub section  Hypothalamic and anterior pituitary hormones and anti-oestrogens to top
    06.05.01  Expand sub section  Anti-oestrogens
    Clomifene Citrate
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • For ovulation induction
  • On specialist recommendation 
  •    
    06.05.01  Expand sub section  Anterior pituitary hormones
    Choriogonadotropin Alfa (Ovitrelle®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Hospital only 
  •    
    Human Chorionic Gonadotrophin
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Human Menopausal Gonadotrophins
    (menotrophin)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Somatropin
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
     
    Link  NICE TA188: Human growth hormone (somatropin) for the treatment of growth failure in children (review)
    Link  NICE TA64: Growth hormone deficiency (adults) - human growth hormone
       
    Tetracosactide (Synacthen®, Synacthen Depot® )
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.05.01  Expand sub section  Hypothalmic hormones
    Protirelin (TRH)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.05.02  Expand sub section  Posterior pituitary hormones and antagonists
    06.05.02  Expand sub section  Posterior pituitary hormones to top
    Desmopressin
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
  • Tablets
  • Melts (60mcg, 120mcg and 240mcg only)£££
  • Nasal solution
  • Nasal spray (10mcg/dose) 
  •    
    06.05.02  Expand sub section  Antidiuretic hormone antagonists
    Demeclocycline (capsules)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • in the treatment of hyponatraemia resulting from inappropriate secretion of antidiuretic hormone. UNLICENSED 
  •    
    Tolvaptan (Jinarc®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • In line with NICE 
  • Link  NICE TA 358:Tolvaptan for treating autosomal dominant polycystic kidney disease
       
    Tolvaptan (Samsca®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Currently NOT ROUTINELY COMMISSIONED BY NHS ENGLAND for the treatment of adult patients with hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH).
     
  • Link  Drug safety update: tolvaptan (Samsca) -risk of liver injury
    Link  MHRA Warning
       
    06.06  Expand sub section  Drugs affecting bone metabolism
    06.06  Expand sub section  Osteoporosis
    06.06.01  Expand sub section  Calcitonin and parathyroid hormone
    Calcitonin (salmon) / Salcatonin
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Injection
  • Nasal spray 
  •    
    Parathyroid Hormone
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • Injection 
  •    
    Teriparatide (Forsteo®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
    High Cost Medicine
  • In line with NICE 
  •    
    06.06.02  Expand sub section  Bisphosphonates and other drugs affecting bone metabolism to top
    06.06.02  Expand sub section  Bisphosphonates
    Alendronic Acid tablets
    View adult BNF View SPC online View childrens BNF
    First Choice
    Green
     
    Risedronate
    View adult BNF View SPC online View childrens BNF
    Second Choice
    Green
     
       
    Alendronic Acid  (Binosto®)
    (70mg effervescent tablets)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Green
  • £££

  • Third line option in individuals who have not tolerated first line alendronate tablets and second line risedronate tablets and in whom a bone-sparing agent is still considered clinically necessary.
     
  •    
    Disodium Pamidronate
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Ibandronic Acid 150mg
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • Supported by an ESCA (in development) 
  •    
    Ibandronic Acid 50mg
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • For skeletal events in metastatic breast cancer.
  • Supported by an ESCA, see link below. 
  • Link  ESCA: Ibandronic acid 50mg
       
    Ibandronic Acid injection
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Sodium Clodronate
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • For the management of osteolytic lesions, bone pain and hypercalcaemia associated with multiple myeloma or breast cancer.
  • Supported by an ESCA, see link below. 
  • Link  ESCA: Sodium clodronate
       
    Zoledronic Acid
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.06.02  Expand sub section  Denosumab
    Denosumab (Prolia®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Amber
  • Use in postmenopausal osteoporosis is supported by an ESCA, see link below. 
  • Link  ESCA: Denosumab
    Link  NICE TA204: Osteoporotic fractures - denosumab
       
    Denosumab (XGEVA®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
    Link  NICE TA265: Bone metastases from solid tumours - denosumab
       
    06.06.02  Expand sub section  Strontium renelate
    06.07  Expand sub section  Other endocrine drugs
    06.07.01  Expand sub section  Bromocriptine and other dopaminergic drugs to top
    Bromocriptine
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Cabergoline
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    Formulary
    Amber
     
       
    Quinagolide
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    Formulary
    Amber
     
       
    06.07.02  Expand sub section  Drugs affecting gonadotrophins
    Cetrorelix (Cetrotide®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    Danazol
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    Formulary
    Amber
  • For hereditary angioedema (off label use) 
  •    
    06.07.02  Expand sub section  Gonadorelin analogues
    Buserelin
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
  • For assisted conception
     
  •    
    Buserelin nasal spray
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    Formulary
    Red
  • For assisted conception
     
  •    
    Goserelin
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    Formulary
    Red
  • For assisted conception 
  •    
    Goserelin
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    Formulary
    Amber
  • For endometriosis or breast cancer
  • Specialist initiation
     
  • Link  CKS guideline: Management of confirmed endometriosis- Secondary Care treatments
       
    Leuprorelin
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    Formulary
    Amber
  • For endometrosis or breast cancer
  • Specialist initiation
     
  • Link  CKS guideline: Management of confirmed endometriosis- Secondary Care treatments
       
    Triptorelin
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    Formulary
    Amber
  • For endometriosis
  • Specialist initiation
     
  • Link  CKS guideline: Management of confirmed endometriosis- Secondary Care treatments
       
    06.07.02  Expand sub section  Breast pain (mastalgia)
    06.07.03  Expand sub section  Metyrapone
    Metyrapone (Metopirone®)
    View adult BNF View SPC online View childrens BNF
    Formulary
    Red
     
       
    06.07.04  Expand sub section  Somatomedins to top
    Mecasermin (Increlex®)
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    Formulary
    Red
  • NHSE commissioned. 
  •    
     ....
     Non Formulary Items
    Acarbose  (Glucobay®)

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    Non Formulary
    Black
    For existing patients only.
     
    Alendronic Acid
    (oral solution )

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    Non Formulary
    Black
  • Removed from formulary in December 2016, replaced by effervescent tablets.
  •  
    Alendronic Acid with colecalciferol  (Fosavance®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Alogliptin / metformin  (Vipdomet®)

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    Non Formulary
     
    Alogliptin / pioglitazone  (Incresync®)

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    Non Formulary
     
    Armour thyroid®

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    Non Formulary
    Black
    Link  Patient Information Leaflet
    Link  UKMI Q&A: What clinical evidence is there to support the use of “Armour thyroid” or desiccated thyroid extract?
     
    Biphasic Isophane Insulin  (Hypurin® Porcine 30/70 Mix)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Chlorpropamide

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    Non Formulary
     
    Combination test strips

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    Non Formulary
     
    Corifollitropin Alfa  (Elonva®)

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    Non Formulary
     
    Cortisone Acetate

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    Non Formulary
     
    Dapagliflozin / metformin  (Xigduo®)

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    Non Formulary
     
    Deflazacort  (Calcort®)

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    Non Formulary
     
    Desmopressin  (Noqdirna ®)

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    Non Formulary
    Black
    25mcg, 50mcg oral lyophilisate
     
    Desmopressin  (Octim®)

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    Non Formulary
     
    Diazoxide  (Eudemine®)

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    Non Formulary
     
    Dienogest

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    Non Formulary
     
    Dydrogesterone  (Duphaston®)

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    Non Formulary
     
    Dydrogesterone  (Duphaston® HRT)

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    Non Formulary
    Black
     
    Flash glucose monitoring system  (FreeStyle Libre®)

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    Non Formulary
    Black
    Please refer to
    BSSE APC INTERIM Position Statement


    The APC is mindful of the RMOC statement and will be actively considering its implications for this health economy, as will commissioners.
    Link  BSOL CCG Policy for the prescribing of Flash Glucose Monitoring
    Link  Regional Medicines Optimisation Committee FreeStyle Libre Position Statement
     
    Follitropin Alfa  (Gonal-F®)

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    Non Formulary
     
    Follitropin Alfa and Beta  (Puregon®)

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    Non Formulary
     
    Ganorelix  (Orgalutran®)

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    Non Formulary
     
    Gestrinone  (Dimetriose®)

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    Non Formulary
     
    Glipizide

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    Non Formulary
    Black
     
    Gliquidone  (Glurenorm®)

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    Non Formulary
     
    Glucose  (Clinistix®)

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    Non Formulary
     
    Glucose  (Clinitest®)

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    Non Formulary
     
    Glucose  (Diabur-Test® 5000)

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    Non Formulary
     
    Glucose  (Diastix®)

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    Non Formulary
     
    Glucose test strips

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    Non Formulary
     
    Human Menopausal Gonadotrophins  (Menogon®)

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    Non Formulary
     
    Hydrocortisone MR  (Plenadren)

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    Non Formulary
     
    Hydrocortisone sodium phosphate  (Efcortesol®)

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    Non Formulary
     
    Insulin  (Exubera®)

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    Non Formulary
     
    Insulin  (Pork Actrapid®)

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    Non Formulary
     
    Insulin  (Velosulin®)

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    Non Formulary
     
    Insulin 500 units in 1mL  (Humulin R®)

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    Non Formulary
     
    Insulin bovine  (Hypurin® Bovine Neutral)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Insulin degludec 200 units/mL  (Tresiba®)

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    Non Formulary
     
    Insulin degludec and liraglutide  (Xultophy®)

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    Non Formulary
     
    Insulin Lispro 200 units/mL  (Humalog 200 units/mL ®)

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    Non Formulary
     
    Insulin porcine  (Hypurin® Porcine Neutral)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Insulin Zinc suspension  (Hypurin®Bovine Lente)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Isophane Insulin  (Hypurin® Bovine Isophane)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Isophane Insulin  (Hypurin® Porcine Isophane)

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    Non Formulary
    Black
  • For existing patients only
  •  
    Isophane Insulin  (Pork Insulatard®)

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    Non Formulary
     
    Ketones  (Ketur Test®)

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    Non Formulary
     
    Ketones test strips

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Linagliptin/ metformin  (Jentadueto®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Liraglutide  (Saxenda®)

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    Non Formulary
  • For weight loss/ obesity
  • No application received by APC yet
  •  
    Lutropin Alfa  (Luveris®)

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    Non Formulary
     
    Mesterolone  (Pro-Viron®)

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    Non Formulary
     
    Metformin & pioglitazone  (Competact®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Nafarelin

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    Non Formulary
     
    Nateglinide  (Starlix®)

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    Non Formulary
    Black
    For existing patients only
     
    Norethisterone  (Micronor® HRT)

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    Non Formulary
     
    Pasireotide

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    Non Formulary
     
    Pegvisomant  (Somavert®)

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    Non Formulary
     
    Pioglitazone and Metfomin  (Competact®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Prednisone MR

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Protamine Zinc Insulin  (Hypurin® Bovine Protamine Zinc)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
  • For existing patients only
  •  
    Protein  (Medi-Test® Protein 2)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Protein test strips  (Albustix®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Rosiglitazone  (Avandia®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Rosiglitazone and Metformin  (Avandamet®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Saxagliptin  (Onglyza®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
     
    Saxagliptin and metformin  (Komboglyze®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Sermorelin  (Geref 50®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Sitagliptin and Metformin  (Janumet®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Strontium Ranelate

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
  • Discontinued August 2017
  • Link  Discontinuation of Protelos (strontium ranelate) 2g granules for oral suspension
     
    Test Strips  (Combur 9®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Combur5® )

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Combur7®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Diastix®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Keto-Diastix®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Multistix 10 SG®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Multistix 8SG®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Multistix SG®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Test Strips  (Multistix®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters  (Andropatch®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters  (Intrinsa®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters  (Striant® SR)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters  (Sustanon 100®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Testosterone and Esters  (Virormone®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Thyrotropin Alfa  (Thyrogen®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Tiludronic Acid  (Skelid®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Tolbutamide

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
     
    Trilostane  (Modrenal®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
     
    Urinalysis  (Clinitest®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Urofollitropin

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Vasopressin  (Pitressin®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
     
    Vildagliptin

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Black
     
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Green

    Medicines which are suitable for initiation and maintenance prescribing by primary and secondary care clinicians. These medicines should be initiated and prescribed within their licensed indications.  

    Amber

    Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate, or initiation and maintenance of prescribing in Primary Care following recommendation from a Specialist.

    Some amber medicines require agreement with the local (internal) medicines committee prior to initiation; others may require a framework to support safe transfer and maintenance of care such as a RICaD or ESCA. The Formulary will be annotated to reflect these requirements.   

    Red

    Medicines for initiation and maintenance prescribing by Specialists only  

    Black

    Non-formulary medicines- medicines not recommended for routine primary care prescribing.  

    Grey

    Positive NICE TA and /or awaiting local clarification on place in therapy ; Please contact your Medicines Optimisation team for more information.  

    netFormulary